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. 2016 Jan 26;63(4):1256–1271. doi: 10.1002/hep.28417

Figure 5.

Figure 5

ACTL6A promotes invasion, metastasis, and EMT through Notch signaling. (A) Migration and invasion assays for PLC/PRF5‐ACTL6A, Hep3B‐shACTL6A and their control cells with/without DAPT treatment. (B) IF assay of E‐cadherin and vimentin expressions in PLC/PRF5‐ACTL6A, Hep3B‐shACTL6A, and their control cells with/without DAPT treatment. (C) EMT‐related protein expression in PLC/PRF5‐ACTL6A, Hep3B‐shACTL6A, and their control cells with/without DAPT treatment. (D) Representative IHC images of ACTL6A, NICD1, vimentin, E‐cadherin, and snail expression in liver orthotopic transplantation tumor generated from PLC/PRF5‐ACTL6A, Hep3B‐shACTL6A and their control cells; magnification: 400×.