Table 2.

MTR_asym (3.5 ppm) values (mean ± 95% CI) of bilateral Hc, TWM, OWM, and CP in normal controls and AD patients

	Control subjects (n = 20)	Patients with AD (n = 20)	t	P
Right Hc	0.83 ± 0.19	1.24 ± 0.21	3.039	0.004*
Left Hc	0.80 ± 0.17	1.18 ± 0.18	3.238	0.002*
Right TWM	0.39 ± 0.08	0.42 ± 0.09	0.636	0.529
Left TWM	0.34 ± 0.06	0.38 ± 0.10	0.699	0.489
Right OWM	0.32 ± 0.07	0.36 ± 0.12	0.591	0.558
Left OWM	0.38 ± 0.09	0.34 ± 0.09	0.604	0.549
Right CP	1.03 ± 0.15	1.14 ± 0.22	0.778	0.442
Left CP	1.09 ± 0.19	1.19 ± 0.21	0.703	0.487

*Significant change. CI: Confidence interval; AD: Alzheimer’s disease’; CP: Cerebral peduncles; OWM: Occipital white matter; TWM: Temporal white matter; Hc: Hippocampus; MTR_asym: Magnetic resonance ratio asymmetry.