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Intraplantar BiTox transiently reduced CFA-induced mechanical but not thermal hypersensitivity. Intraplantar injection of BiTox given 24 hours after IPLT injection of CFA transiently reduced mechanical (A) but not thermal hypersensitivity (B) on days 2 and 3 post-BiTox injection. Baseline pain threshold (BL) was determined for 5 days before injection. Data are presented as means ± SEM, *P > 0.05, **P < 0.01. n = 6 to 8 animals per group.
