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Reduced incorporation of BrdU into keratinocytes after IPLT BiTox treatment. Photomicrographs from sections of cutaneous tissue (A) 14 days after vehicle or (B) BiTox IPLT pretreatment. There was a significant reduction of BrdU positive keratinocytes 14 days or 32 days but not 3 days after BiTox pretreatment (C). Scale bar = 60 μm. Arrows point to BrdU labeled cells in the basal epidermis. Data are presented as means ± SEM, *P < 0.05. n = 3 to 4 animals per group.
