Table 1.

Parameters values and derived quantities for the humanized mouse experiments by the Bayesian inference

Strain [best fit value (95 % CI)]	$T\left(0\right)$ (cells/ml)	$V\left(0\right)$ (RNA copies/ml)	$\mathit{\beta }$ [(virion/ml)−1 day−1 (×10−7)]	$\mathit{\delta }$ (day−1)	$r$ † [(cell/ml)−1 day−1 (×10−6)]	$R_0$ ‡ (–)
WT HIV-1	84,621 (66,301–105,897)	1324 (925–1837)	4.41 (2.58–6.78)	0.428 (0.261–0.699)	11.50 (7.79–16.84)	2.29 (1.75–2.90)
HIV-1Δvpu					9.97 (6.59–15.06)	1.97 (1.58–2.44)

^† $p=0.138$ by the repeated bootstrap t test and Cohen’s $d=0.664$ (statistical power $=0.290$) between WT HIV-1 and HIV-1Δvpu. 10 parameter sets are sampled from the posterior predictive distribution

^‡ $p=0.035$ by the repeated bootstrap t test and Cohen’s $d=1.395$ (statistical power $=0.839$) between WT HIV-1 and HIV-1Δvpu. 10 parameter sets are sampled from the posterior predictive distribution