Table 1.
Baseline characteristics of the patients in two subtypes of microscopic colitis a
| Histological subtype | P value | |||
|---|---|---|---|---|
| Lymphocytic colitis (n=55) | Collagenous colitis (n=76) | |||
| Age (years) | Mean (SD) | 59.9 (20.8) | 61.3 (15.1) | 0.72 |
| BMI (Kg/m2) | Mean (SD) | 25.8 (5.2) | 24.7 (4.6) | 0.38 |
| Sex | ||||
| Female | %(n) | 69.1 (38) | 85.5 (65) | 0.03 |
| Race | ||||
| White | %(n) | 90.9 (50) | 94.7 (71) | 0.49 |
| Abdominal Pain | %(n) | 41.8 (23) | 32.0 (24) | 0.27 |
| Weight Loss | %(n) | 27.3 (15) | 30.7 (23) | 0.70 |
| Type 2 Diabetes | ||||
| Mellitus | %(n) | 18.2 (10) | 5.3 (4) | 0.02 |
| Autoimmune disease | %(n) | 41.8 (23) | 42.7 (32) | 1.00 |
| Hashimoto’s disease | 47.8 (11) | 37.5 (12) | 0.58 | |
| Celiac disease | 17.4 (4) | 28.1 (9) | 0.52 | |
| Othersb | 60.9 (14) | 59.4 (19) | 1.00 | |
| GERD | %(n) | 38.2 (21) | 41.3 (31) | 0.86 |
| Smoke | %(n) | 23.6 (13) | 15.8 (12) | 0.27 |
| ESR (mm/h) | Mean (SD) | 13.3 (19.3) | 28.2 (18.6) | 0.04 |
| SSRIsc | %(n) | 36.4 (20) | 27.8 (20) | 0.34 |
| NSAIDsc | %(n) | 38.2 (21) | 54.9 (39) | 0.07 |
| Antibioticsc | %(n) | 16.4 (9) | 20.8 (15) | 0.65 |
| PPIsc | %(n) | 38.2 (21) | 34.7 (25) | 0.71 |
| Statinsc | %(n) | 21.8 (12) | 23.6 (17) | 0.83 |
a
Abbreviations: SD = Standard deviation; GERD = Gastro esophageal reflux; ESR = Erythrocyte sedimentation rate; SSRIs = Selective serotonin reuptake inhibitors; NSAIDs = Non-steroidal anti-inflammatory drugs; PPIs = Proton pump inhibitors.
b
Psoriasis, Type 1 Diabetes Mellitus, Rheumatoid arthritis, Grave’s disease, Sjögren’s disease, and unspecified immune disease disorder.
c
Defined as use up to one month prior to onset of symptoms.