Table 3.

Estimated Proportion of Expected Live Births with Symptomatic Congenital or Acquired CMV Disease Identified in California NICUs, 2005–2010

	n
Total number of live births in California during 2005–2010	3 272 565
Number of VLBW live births	38 539
Expected number of live births in California with
Symptomatic congenital CMV disease (LB*0.7%*12.7%)§	2909(a)
Symptomatic acquired CMV disease among VLBW live births (VLBW*2.4%)¥	925(b)
Total number of live births with either symptomatic congenital or acquired CMV disease	3834(a+b)
Number of live births reported with CMV infection in CPQCC-member NICUs	156
Number of live births identified with CMV infection in California NICUs extrapolated from CPQCC£	179(c)
Proportion of expected number of live births with symptomatic congenital or acquired CMV disease identified in California NICUs	5%(c/(a+b))

Notes:

^§Estimates of birth prevalence of congenital CMV infection and proportion of symptomatic infants at birth according to a published systematic review of the literature [6]

^¥Estimates of postnatal CMV disease acquired via consumption of frozen breast milk [17]

^£Based on average CPQCC coverage of 87% during 2005–2010