Table 1.
Comparisons of demographic information, vascular diseases and lipid profiles across amylin quartiles
| Amylin quartiles | Quartile 1 n = 276 |
Quartile 2 n = 277 |
Quartile 3 n = 277 |
Quartile 4 n = 276 |
|---|---|---|---|---|
| Age, year, mean±SD | 75.5±8.7 | 75.0±8.4 | 75.1±8.5 | 74.2±8.5 |
| Female, n/total (%) | 213/276 (77%) | 204/277 (74%) | 214/277 (77%) | 212/276 (77%) |
| African Americans, n/total (%) | 108/275 (39%) | 95/276 (34%) | 95/275 (35%) | 90/275 (33%) |
| High School Graduate and above, n/total (%) | 170/275 (62%) | 174/276 (63%) | 185/274 (68%) | 180/275 (65%) |
| Body mass index, Mean±SD** | 30.0±8.4 | 31.4±9.0 | 32.0±7.6 | 32.9±9.1 |
| ApoE4 carriers, n/total (%) | 63/272 (23%) | 61/275 (22%) | 68/275 (25%) | 65/271 (24%) |
| Vascular Diseases | ||||
| Diabetes, n/total (%)* | 97/265 (37%) | 87/269 (32%) | 92/268 (34%) | 117/265 (44%) |
| Stroke, n/total (%) | 54/265 (20%) | 61/272 (22%) | 53/270 (20%) | 50/268 (19%) |
| Creatinine, mg/dL, mean±SD*** | 0.90±0.68 | 0.93±0.92 | 1.05±0.74 | 1.39±1.53 |
| Lipid Profile | ||||
| Cholesterol, mg/dL, Mean±SD** | 183.8 ± 46.3 | 183.8 ± 41.3 | 192.1±43.9 | 179.0±40.2 |
| LDL, mg/dL, mean ± SD** | 106.7±38.1 | 108.1±35.1 | 112.4±35.6 | 100.9±33.5 |
| HDL, mg/dL, mean ± SD*** | 53.6 ± 16.6 | 49.3 ± 13.7 | 49.2 ± 14.7 | 46.6 ± 13.4 |
Mean±SD with ANOVA test or n/total with Chi-Square test is used to describe the distributions and comparisons of age, diseases, kidney function assessed by the measurement of creatinine and the lipid biomarkers across the amylin quartiles.
*
p< 0.05,
**
p< 0.001,
***
p< 0.0001 for the statistical significance are shown. LDL, low density lipoprotein; HDL, high density lipoprotein.