. Author manuscript; available in PMC: 2016 Apr 18.

Published in final edited form as: J Alzheimers Dis. 2014;42(2):555–563. doi: 10.3233/JAD-140210

Table 3.

Effects of plasma amylin on cognitive tests in multivariate regression analyses

Outcomes	Log₁₀ Amylin
	Model I Adjusting for age, gender, ethnicity, school, and ApoE4		Model II Model I plus BMI, diabetes, stroke, kidney function, and lipid profile
	Estimate β (SE)	p value	Estimate β (SE)	p value
MMSE Scores	+0.111 (0.086)	0.20	+0.143 (0.096)	0.14
Verbal fluency	+0.212 (0.318)	0.50	+0.336 (0.359)	0.35
Digit span	+0.019 (0.095)	0.84	+0.081 (0.108)	0.45
WLL delayed recall	+0.032 (0.072)	0.66	+0.063 (0.083)	0.45
LM delayed recall	+0.492 (0.248)	0.05	+0.620 (0.277)	0.03
Trailmaking A	−6.077 (1.541)	<0.0001	−4.810 (1.653)	0.004
Trailmaking B	−4.243 (2.075)	0.04	−3.462 (2.335)	0.14
Block design	+0.634 (0.230)	0.006	+0.520 (0.258)	0.04

Plasma amylin was transformed to log₁₀ (Log₁₀ Amylin) as a determining factor. The lipid profile includes cholesterol, LDL, and HDL. MMSE, Mini-Mental State Exam; WLL, Word learning list; LM, Logical memory.