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. Author manuscript; available in PMC: 2016 May 18.
Published in final edited form as: Kidney Int. 2015 Sep 9;88(6):1402–1410. doi: 10.1038/ki.2015.239

Figure 2. Expression of KIF12 and DLG1 in the developing human kidney.

Figure 2

Transversal section through lumbosacral part of human embryo (6th week of development): a) within the nephrogenic zone (nz), KIF12 is weakly expressed in the developing nephron (renal vesicle – rv) and negative in the metanephric mesenchyme (mm). KIF12 is strongly expressed (arrows) in the UB stalk and UB-derived structures, such as the epithelium of collecting ducts (Cd), while the surrounding mesenchyme is negative; b) DAPI nuclear staining; c) merge of a and b; negative isotype control. d) DLG1 is weakly or not expressed in the developing nephron (renal vesicle – rv, metanephric cup - mc) and negative in the metanephric mesenchyme (mm), while it is moderately expressed (arrows) in the epithelium of collecting ducts (Cd); e) DAPI nuclear staining; f) merge of d and f; negative isotype control. Immunostaining of Kif12 and Dlg1, magnification ×40, scale bar 25Xm.