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. 2015 Dec 29;6(1):e00424. doi: 10.1002/brb3.424

Table 3.

Regions with highest Z value appearing in the contrasts healthy controls (CTR) more than vegetative state/unresponsive wakefulness syndrome patients (VS/UWS) and preserved in vegetative state/unresponsive wakefulness syndrome patients for the three cases of FDG‐PET, fMRI total neuronal and conjunction analyses of FDG‐PET and fMRI. Regions with highest Z values corresponding to a higher decrease in FDG‐PET with respect to fMRI total neuronal and with a higher decrease in fMRI total neuronal with respect to FDG‐PET (for the contrast healthy controls more than vegetative state/unresponsive wakefulness syndrome patients). Regions are shown in talaraich space

Brain region X, Y, Z T (df = 51) P (FDR‐corr)
FDG‐PET (CTR > VS/UWS)
Superior gyrus −17, 11, 58 3.9 <0.001
Medial frontal cortex 1, 43, 28 3.7 <0.001
Precuneus 0, −64, 36 7.0 <0.001
FDG‐PET (Preserved)
Brainstem 1, −29, −18 4.7 <0.001
fMRI total neuronal (CTR > VS/UWS)
Intraparietal cortex −57, 52, 25 3.7 <0.001
Temporal cortex Left/Right 62, −23, −17 3.3 <0.001
Medial orbitofrontal cortex 0, 45, −10 3.8 <0.001
fMRI total neuronal (Preserved)
Hipothalamus −1.8, −3.5, −7.5 3.9 <0.001
PET‐fMRI conjunction (CTR > VS/UWS)
Precuneus −0, −56, 13 2.9 <0.001
Intraparietal cortex 46, −40, 46 3.7 <0.001
Inferior frontal gyrus Left/Right −54, 13, 15 2.0 <0.001
Medial frontal gyrus Left/Right −48, 12, 26 2.3 <0.001
PET > fMRI (CTR > VS/UWS)
Precuneus −0.9, −65, 43 3.2 <0.001
Insula −43, 19, −3 3.6 <0.001
Caudate 13, 6, 12 5.0 <0.001
Thalamus −8, −26, 6 4.0 <0.001
PET < fMRI (CTR > VS/UWS)
Medial prefrotal cortex 6, 40, −7 3.8 <0.001
Brainstem 4, −4, 21 3.6 <0.001
Amigdala 30, −7, 21 4.0 <0.001

FDG‐PET, 18F‐fluorodeoxyglucose positron emission tomography; fMRI, functional magnetic resonance imaging.