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. 2015 Sep 21;17(2):205–220. doi: 10.1093/biostatistics/kxv038

Table 5.

Estimated regression coefficients for some selected SNPs in the SMA model

SNP Annotation Gene MESA-A CARDIA-A CHS-A MESA-E CARDIA-E CHS-E FHS
rs4420638 Downstream APOC1 0.03 Inline graphic0.03 Inline graphic0.19 Inline graphic0.26 Inline graphic0.49
rs660240 3Inline graphicUTR CELSR2 0.24 0.07 0.26 0.22 Inline graphic0.15
rs445925 Upstream APOC1 Inline graphic0.03 Inline graphic0.17 Inline graphic0.25 Inline graphic0.32 Inline graphic0.31 Inline graphic0.42
rs6511720 Intron LDLR 0.16 0.23 0.16 0.20 0.28 0.38
rs964184 Downstream ZPR1 0.08 Inline graphic0.24 Inline graphic0.12 Inline graphic0.15
rs2954021 Intron LOC105375745 0.03 0.15 0.10 0.07
rs9302635 Intron DHX38 Inline graphic0.07 Inline graphic0.05 Inline graphic0.02 Inline graphic0.10
rs7254892 Intron PVRL2 Inline graphic0.49
rs13414987 Downstream APOB
rs520861 Downstream TDRD15 Inline graphic0.23 Inline graphic0.25 Inline graphic0.04 Inline graphic0.10 Inline graphic0.10 Inline graphic0.14
rs4803770 Downstream APOC1 Inline graphic0.10 Inline graphic0.16 Inline graphic0.02
rs2867314 Intron LUZP1 0.09
rs1367117 Missense APOB 0.13 0.11 0.17
rs9939224 Intron CETP Inline graphic0.23
rs6669785 Intron LEPR Inline graphic0.13
rs4148817 Intron ABCB4 Inline graphic0.10
rs38117588 Intron Ipcef1 Inline graphic0.08
rs12357364 Intron RNLS 0.07
rs1544410 Upstream VDR 0.09
rs4384362 Intron PDGFD Inline graphic0.16
rs1002054 Intron MAPK1IP1L Inline graphic0.16
rs1470641 Intron ITPR2 Inline graphic0.18 Inline graphic0.07 0.20
rs3846662 Intron HMGCR Inline graphic0.14 Inline graphic0.05 Inline graphic0.05 Inline graphic0.04 Inline graphic0.14
rs12982656 Intron INSR 0.03 0.17 0.08

Note: Zero estimates are left blank. Annotation is based on dbSNP (http://www.ncbi.nlm.nih.gov/snp).