Fig 1. RCM features used in identification of the start and end of each anatomical strata.

A) The start of the viable epidermis is marked by the first visible honeycomb pattern (Blue outline). B) The start of the dermal-epidermal junction is marked by the first clearly defined papillae with bright ring of basal cells surrounding a dark centre (Blue arrows). C) The start of the papillary dermis is marked by the absence of features corresponding to the basal layer. D) Alternative definition of the start of the dermal-epidermal junction for light skin types, a dark featureless patch surrounded by keratinocytes with the absence of a bright basal layer (Blue arrow).