. 2016 Apr 18;11(4):e0153472. doi: 10.1371/journal.pone.0153472

Table 2. Plasma ion, aldosterone and renin activity measurements in C57BL/6N and C57BL/6J male mice.

Strain	Diet	n	Na⁺	K⁺	Cl^-	Mg²⁺	Aldosterone	Renin activity
			mmol/l	mmol/l	mmol/l	mmol/l	pg/ml	ng/ml/hr
C57BL/6N	NS	9	150.2±0.4	4.2±0.1	114.3±0.4	0.99±0.03	336±51	80±5
	LS	9	150.1±0.5	4.0±0.2	112.0±0.4^*	0.87±0.02^*	541±61^*	177±33^*
	HS	8	148.6±0.5	4.5±0.2	113.6±0.3	0.97±0.03	≤36^*	48±5 ^*
	HS/LK	8	151.3±0.7	4.3±0.2	112.5±1	1.04±0.04	≤36^*	34±6^*
C57BL/6J	NS	10	151.5±0.4	4.5±0.1	117.1±0.7	1.00±0.03	272±16	76±16
	LS	10	150.0±0.4	4.1±0.1	114.1±0.7^*	0.91±0.03	562±52^*	174±21^*
	HS	9	149.3±0.5^*	4.5±0.2	114.5±0.4^*	0.94±0.04	66±4^*	38±5^*
	HS/LK	8	150.5±0.6	3.3±0.3^*	114.6±0.9^*	1.01±0.03	75±4^*	12±2^*

Plasma ion measurements performed on a third and separate cohort of 18 C57BL/6N and 20 C57BL/6J male mice, under a modified light/dark cycle. NS = normal salt diet, LS = low salt diet, HS = high Na+/normal K+ diet and HS/LK = high Na+/low K+ diet. Data represented as mean +/- SEM. One-way ANOVA per strain followed by Tukey’s post-hoc test

*: p<0.05 compared to NS diet.