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. Author manuscript; available in PMC: 2017 Mar 1.
Published in final edited form as: Angew Chem Int Ed Engl. 2016 Feb 5;55(10):3309–3312. doi: 10.1002/anie.201509183

Figure 4.

Figure 4

(a) Fluorescence images of sections of mouse intestine after administration of BSA- or Tf-coated NPs (red). Cell nuclei were stained with DAPI (blue); (b) Blood glucose response of normal rats to free insulin or insulin released from the NPs (2 U/kg) (n = 4); (c) Blood glucose response of normal rats to free insulin solution, BSA-coated NPs, and Tf-coated NPs with different formulations following oral gavage (n = 6); (d) Blood glucose response of diabetic mice to free insulin solution, BSA-coated NPs, and Tf-coated NPs following oral administration (n = 6, * p<0.05 vs. free insulin).