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. Author manuscript; available in PMC: 2017 Apr 1.
Published in final edited form as: Bone. 2016 Feb 3;85:123–130. doi: 10.1016/j.bone.2016.01.023

Fig. 2. PTH increased phosphorylation of β-catenin at ser552 and ser675 in the presence of Cox2 KO CM but not WT CM.

Fig. 2

CM was collected from either the WT BMMs (WT CM) or the Cox2 KO BMMs (KO CM) that were stimulated with Rankl for 3 days. Cox2 KO POBs were treated with vehicle or PTH (10 nM) on day 5 of culture and Western analysis was performed. (A) Time course examining effects of PTH on β-catenin phosphorylation. (B–E) Densitometry of bands was performed and normalized to β-actin. Vehicle-treated WT CM was set to 1. Bars represent means ± SEM, n=4. aSignificant effect of PTH, p<0.01; bp<0.05. cSignificant difference compared to WT CM, p<0.01; dp>0.05.