Figure 1.

Photomicrograph of the ventrolateral preoptic area (VLPO) of a control brain, with neurons immunolabeled for galanin (A). The number of galaninergic VLPO neurons is similar in narcolepsy patients and controls, whereas the number of orexin neurons was significantly reduced and the number of histaminergic TMN neurons was significantly increased in narcolepsy patients compared to controls (B). *P < 0.001. 3V, third ventricle; OT, optic tract; PVN, paraventricular nucleus; SON, supraoptic nucleus. Scale bar, 1 mm.