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. 2016 Apr 19;6:44. doi: 10.3389/fcimb.2016.00044

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Copyright © 2016 Gao, Tan, Liu, Zhang, Zhang, Zheng, Zhu, Li and Zhou.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Mouse infection experiments. (A) Survival curves for mice in experiment infection. Ten mice in each group were separately injected intraperitoneally i with 3 × 10⁹ CFU/mice of SC-19 and ΔgidA. Ten mice were inoculated with saline and served as negative control. Significant difference in survival between different groups were analyzed by Log Rank test (p < 0.05). (B) Bacteria loads in (B) brain, (C) lung, and (D) in spleen. The SC-19 and ΔgidA mutant strains were distinguished by erythromycin added in the TSA plates. Statistical significance was determined by two-tailed t-test (ns, p > 0.05; ^*p < 0.05; ^**p < 0.01; ^***p < 0.001).