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Doses of radioligands used in animal PET studies
| Radioactivity (MBq) | Pharmacological dose (nmol) | |||
|---|---|---|---|---|
| Total (n) | Low dose group (n) | High dose group (n) | ||
| [11C](R)-PK11195 | 28.9 ± 6.6 | 2.41 ± 4.11 (9) | 0.36 ± 0.28 (4) | 4.45 ± 5.25 (5) |
| [11C]CB184 | 29.1 ± 5.6 | 1.39 ± 1.96 (10) | 0.19 ± 0.11 (5) | 2.60 ± 2.23 (5) |
Radioactivity and pharmacological dose of [11C](R)-PK11195 and [11C]CB184 were indicated. Data represent mean and SD. Number of animals was shown in the parenthesis
