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. 2016 Mar 1;131:753–773. doi: 10.1007/s00401-016-1551-3

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© The Author(s) 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 7 — Analysis of stroke severity in Ang-2 GOF mice. a pMCAO infarcts were larger in GOF (24 h, WT, GOF n = 4; 72 h, WT n = 10, GOF n = 7; 7 days, WT, GOF n = 5). b IgG permeability in the infarct area was higher in GOF (n = 6) compared to WT (n = 4)