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Summary of phenotypes in polymerase variant yeast strains.
| Phenotype | L868M Pol α | L612M Pol δ | M644G Pol ε |
|---|---|---|---|
| RNase H2-Dependent Repair | Yes | Yes | Yes |
| Top1-Dependent Removal | No | No | Yes |
| Phenotypes of rnh201Δ Derivatives | |||
| Doubling time | Normal | Normal | Increased |
| Rate Δ2–5 bp | Wild-type | Wild-type | Elevated |
| HU-Sensitivity | Normal | Normal | Sensitive |
| Viability in rnh1Δ | Viable | Viable | Inviable |
