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. 2016 Apr 26;8(4):158–169. doi: 10.4252/wjsc.v8.i4.158

Figure 1.

Figure 1

Comparison of the T cell receptors and the antigen presenting molecules among αβ T cell subsets. Invariant T cell subsets consist of mucosal-associated invariant T (MAIT) cells and natural killer T (NKT) cells expressing invariant TCRs. MAIT cells and NKT cells recognize vitamin B2 metabolites on MR1, and α-galactosylceramide (α-GalCer) on CD1d, respectively. In contrast, conventional CD8+ and CD4+ T cells possess divergent TCRs and recognize a variety of peptides on major histocompatibility complex-class I and class II, respectively. TCRs: T cell receptors; MHC: Major histocompatibility complex.