Table 1. Reproducibility of the SEVs isolation.

Methods	No.	SEVs protein (μg)	Average	SD	RSD (%)
ACCF method	1	3.876	3.940	0.073	1.85
	2	3.926
	3	4.020
Conventional centrifugation method	1	3.324	3.315	0.094	2.83
	2	3.405
	3	3.216

SEVs were separated from 300 μL saliva sample by ACCF and conventional centrifugation method, respectively.