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. Author manuscript; available in PMC: 2016 Jun 16.
Published in final edited form as: Environ Sci Technol. 2015 Jun 1;49(12):7400–7410. doi: 10.1021/acs.est.5b00977

Table 1.

KEGG Pathway Analyses of Gene Transcription Data Show That Exposure to Flame-Retardants Largely Affected Different Biological Pathwaysa

biological pathways affected by exposure to different chemical flame-retardants

KEGG biological pathway FM550 octaBDE pentaBDE BZ54 BEH-TEBP BEHP
ribosome 0.061 0.030
glycosphingolipid biosynthesis 0.086 0.089
spliceosome 0.066
pyrimidine metabolism 0.002
proteasome 0.074
WNT signaling pathway 0.089
porphyrin and chlorophyll metabolism 0.020 0.026
glycosaminoglycan degradation 0.052
hedgehog signaling pathway 0.052
arginine and proline metabolism 0.083
tyrosine metabolism 0.048 0.042
phenylalanine metabolism 0.044
a

Numbers in this graph represent the p-value of each analysis. Because annotation of the array is limited, p-values up to 0.1 were included.