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. 2016 Apr 18;16:274. doi: 10.1186/s12885-016-2302-5

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© Brodsky et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — ColXα1 IHC scoring is strongly associated with NAC response. a ROC analysis of colXα1 IHC scores, stroma scores, and percent TIL. AUC = Area Under the Curve, SE = Standard Error. b Stroma and sTIL scores did not distinguish responders as strongly as colXα1 IHC. Box and whisker plots of each parameter show distinct separation between tumors that responded to NAC and those that with no response. *P < 0.05, ***P < 0.001