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Compound A does not inhibit large-conductance Ca2+-activated K channel (BK) activity. A: representative BK (Slo1/β1) currents evoked from HEK293 cells at 100 mV. Current traces 1 (control), 2 (10 μM compound A), and 3 [2 mM tetraethylammonium (TEA)] were taken from the time course experiment shown in B where indicated with corresponding numbers.
