Table 3.

Eukaryotic linear motif entries related to the LIR-motif (obtained from http://elm.eu.org/).

ELM identifier	ELM	Description	Status
LIG_LIR_Gen_1	[EDST].{0,2}[WFY]..[ILV]	Canonical LIR motif that binds to Atg8 protein family members to mediate processes involved in autophagy.	ELM
LIG_LIR_Apic_2	[EDST].{0,2}[WFY]..P	Apicomplexa-specific variant of the canonical LIR motif that binds to Atg8 protein family members to mediate processes involved in autophagy.	ELM
LIG_LIR_Nem_3	[EDST].{0,2}[WFY]..[ILVFY]	Nematode-specific variant of the canonical LIR motif that binds to Atg8 protein family members to mediate processes involved in autophagy.	ELM
LIG_LIR_LC3C_4	[EDST].{0,2}LVV	Noncanonical variant of the LIR motif that binds to Atg8 protein family members to mediate processes involved in autophagy.	ELM
LIG_AIM	[WY]..[ILV]	Atg8-family interacting motif found in Atg19, SQSTM1/p62, ATG4B and CALR/calreticulin, involved in autophagy-related processes.	Candidate
LIG_LIR	WxxL or [WYF]xx[LIV]	The LIR might link ubiquitinated substrates that should be degraded to the autophagy-related proteins in the phagophore membrane.	Candidate
LIG_GABARAP	W.FL	GABAA receptor binding to clathrin and CALR; possibly linked to trafficking.	Candidate