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. 2016 Feb 22;12(2):343–356. doi: 10.1080/15548627.2015.1117732

Figure 8.

Figure 8.

Colchicine treatment induces ER stress markers as well as autophagy- and lysosome-related genes. Trout were treated with water or 0.8 mg/kg/d colchicine for one, 2 or 3 d. Hepatic mRNA levels of (A) ER stress-induced genes Ddit3 and Asns, (B) autophagy- related genes Sqstm1, Atg4b, and (C) lysosome- related genes Atp6v1a and Ctsd. Expression values are normalized with Eef1a1-expressed transcripts (*, P < 0.05; n = 6).