Table 1.
Group | Cytokine production (pg/ml) | ||||
---|---|---|---|---|---|
IFN-γ | IL-2 | IL-4 | IL-10 | IL-12 (p70) | |
CDPK6 + ROP18 + PLG | 2092.66 ± 363.69*** | 238.48 ± 6.37*** | >0* | 360.61 ± 296.21 | 4.55 ± 2.91 |
CDPK6 + ROP18 + 206 | 1727.43 ± 506.06** | 257.92 ± 4.04*** | >0* | 520.98 ± 91.89*** | <0 |
CDPK6 + ROP18 | 1835.37 ± 384.89** | 251.35 ± 5.51*** | >0* | 409.57 ± 337.62 | <0 |
ROP18 + PLG | 1720.61 ± 329.18** | 243.76 ± 91.02** | >0* | 56.92 ± 57.09*** | 9.17 ± 15.2 |
ROP18 + 206 | 1595.37 ± 1204.87 | 263.7 ± 30.02*** | >0* | 430.08 ± 623.13 | <0 |
ROP18 | 1530.8 ± 724.92* | 244.52 ± 1.82*** | >0* | 484.58 ± 453.58 | <0 |
CDPK6 + PLG | 1040.08 ± 477.05 | 179.65 ± 107.16 | >0* | 139.41 ± 141.62 | >0 |
CDPK6 + 206 | 1013.52 ± 630.91 | 215.95 ± 43.12*** | >0* | 121.55 ± 103.54 | <0 |
CDPK6 | 838.58 ± 186.37 | 85.66 ± 140.77 | >0* | >0 | <0 |
PBS + PLG | 471.15 ± 232.97 | 45.11 ± 46.95 | 9.29 ± 3.56 | 609.99 ± 267.23 | 6.12 ± 7.25 |
PBS + 206 | 611.01 ± 308.16 | 38.89 ± 35.46 | 13.09 ± 4.67 | 613.01 ± 154.41 | 1.09 ± 2.26 |
PBS | 515.27 ± 363.03 | 20.76 ± 32.26 | 14.73 ± 2.46 | 597.48 ± 216.81 | <0 |
Control | 590.3 ± 257.92 | 33.9 ± 13.16 | 12.43 ± 12.92 | 606.35 ± 376.32 | <0 |
a Splenocytes from mice were harvested 6 weeks after the last immunization
The 4 control groups, PBS + PLG, PBS + 206, PBS, and blank control, were treated as controls in regard to statistical analysis. *P < 0.05. **P < 0.01. ***P < 0.001 compared with the average of the controls