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. 2016 Feb 19;310(8):L733–L746. doi: 10.1152/ajplung.00419.2015

Fig. 2.

Fig. 2.

Fibroproliferative changes are reduced in WT (C57BL/6) mice treated with IL-4 after ALI. A: lung collagen at day 6 following intratracheal (i.t.) LPS (n = 5–6, *P < 0.05). Gene expression for the collagen genes Col1a1 and Col3a1 (B) and the matrix metalloproteinase (MMP) genes Mmp9, Mmp12, and Mmp2 (C) quantified in lung tissue and normalized to Actinb at days 4 and 6 after intratracheal LPS or intratracheal H2O (n = 3–5, *P < 0.05, **P < 0.01, ***P < 0.001 by one-way ANOVA). D: dynamic lung compliance (Crs; ml/cmH2O) and diffusing capacity (DFCO) after intratracheal LPS or intratracheal H2O (n = 8–12, *P < 0.05, ***P < 0.001 by one-way ANOVA).