Table 1. Baseline Patient Characteristics.
Early (n = 25) | Delayed (n = 25) | |
---|---|---|
Age in years, Mean (SD) | 81.9 (7.1) | 80.2 (10.0) |
Gender, Male (n, %) | 17 (68.0) | 13 (52.0) |
Smoking Status (n, %) | ||
Never | 15 (60.0) | 10 (40.0) |
Previous | 8 (32.0) | 14 (56.0) |
Current | 1 (4.0) | 0 (0.0) |
Formal Carer (n, %) | 4 (16.0) | 4 (16.0) |
Informal Carer in Trial (n, %) | ||
None | 6 (24.0) | 12 (48.0) |
Daughter/son | 6 (24.0) | 6 (24.0) |
Partner/Spouse | 11 (44.0) | 6 (24.0) |
Other Family | 2 (8.0) | 1 (4.0) |
Primary Diagnosis (n, %) | ||
ACS | 8 (32.0) | 3 (12.0) |
Heart Failure | 14 (56.0) | 20 (80.0) |
Valvular Disease | 3 (12.0) | 2 (8.0) |
Comorbidities (n, %) | ||
CPD | 6 (24.0) | 8 (32.0) |
CVD | 5 (20.0) | 2 (8.0) |
Cancer | 5 (20.0) | 4 (16.0) |
CKD | 13 (52.0) | 18 (72.0) |
Dementia | 0 (0.0) | 1 (4.0) |
Diabetes | 9 (36.0) | 10 (40.0) |
Liver Disease | 0 (0.0) | 1 (4.0) |
Routine Bloods, (Mean (SD)) | ||
Creatinine (umol/l) | 134.5 (65.0) | 186.9 (120.4) |
Hemoglobin (g/l) | 119.9 (20.7) | 115.4 (19.2) |
Sodium (mmol/l) | 136.5 (5.0) | 137.0 (6.7) |
Urea (mmol/l) | 12.3 (7.0) | 17.1 (8.6) |
eGFR (mls/min) | 50.1 (22.6) | 34.5 (18.6) |
Moderate or Severe LVSD (n, %) | 16 (64.0) | 14 (56.0) |
Co-morbidity score | ||
Karnofsky Score (Mean (SD)) | 62.8 (13.1) | 61.6 (11.8) |
Charlson Comorbidity Index (Mean (SD)) | 3.9 (1.8) | 4.5 (1.5) |
Frail (%) | 13 (52.0) | 15 (60.0) |
Abbreviations: SD, standard deviation; N, number of observations; CKD, chronic kidney disease; CPD, chronic pulmonary disease; CVD, cerebrovascular disease; ACS, acute coronary syndrome; EF, ejection fraction; eGFR, estimated glomerular filtration rate; LVSD, left ventricular systolic dysfunction.