FIG 4.

Comparisons of HI titers and percentages of inhibition with or without oseltamivir against 7 + 1 reverse genetic viruses. (A) Comparisons of HI titers against reverse genetic viruses carrying the pdmH1N1 102/2009-NA wild type (RG-102wt), H275Y mutant (RG-102H275Y), and N2 (RG-N2). HI titers were derived from 4 BAL fluid samples (run in duplicate). HI titers are shown as the geometric mean with 95% CI (*, P < 0.05; ***, P < 0.0001; t test). (B) Comparisons of percentages of neutralization with or without oseltamivir. The neutralization curves were derived from one BAL fluid sample that shows high HI activity. The experiment was run in duplicate, and results are shown as the arithmetic mean ± SEM (***, P < 0.0005; t test).