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DNA sequences of silent mutations in the (pA)p sites. Nucleotide sequences between the VP1 and VP3 start codons were silently mutated to eliminate potentially used (cryptic) PASs (AAUAAA) but still retain the same coding amino acid sequence as the wild type. The mutated sequence is shown with the locations of the 5 PASs (red). The VP1 start codon was mutated from ATG to ACG, together with a weak Kozak signal (GTT AAG), and retained the VP2 start codon, GTG.
