TABLE 2.
Comparison of amino acid sequences of HAs of seal influenza A(H10N7) viruses at different stages of the outbreak
| Influenza A virus | Amino acid at position: |
||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 82 | 94 | 101 | 113 | 119 | 165 | 187 | 204 | 206 | 220 | 236 | 238 | 257 | 264 | 266 | 270 | 321 | 351 | 358 | 379 | 381 | 398 | 482 | 500 | 508 | |
| A/Mallard/NL/1/2014 | E | A | Q | S | G | T | D | Q | N | Q | N | T | K | D | P | N | M | Q | Q | L | E | E | D | V | D |
| A/Seal/Sweden/SVA0546/2014 (April 2014) | E | V | Q | S | G | T | D | Q | N | Q | N | T | R | D | S | N | M | H | L | I | E | D | D | L | D |
| A/harbor seal/Denmark/14-5061-1lu/2014-07 (July 2014) | K | V | Q | N | G | T | N | Q | N | L | K | T | R | E | P | S | V | Q | Q | I | K | D | D | V | D |
| A/Seal/Sweden/SVA0824/2014/H10N7 (August 2014) | K | V | K | N | E | A | D | K | N | Q | K | T | R | E | P | S | V | Q | L | I | E | D | D | L | D |
| A/harbor seal/Germany/S1047_14_L/2014 (October 2014) | K | V | Q | N | G | A | D | K | N | Q/L | K | T | R | E | P | S | V | Q | Q | I | K | D | D | V | N |
| A/harbor seal/NL/PV14-221_ThS/2015 (January 2015) | K | V | Q | N | G | A | D | K | S | L | K | I | R | E | P | S | V | Q | Q | I | K | D | N | V | N |
| Amino acid unique to outbreak strain?a | + (K) | − | − | − | − | − | − | + (K) | − | + (L) | + (K) | + (I) | − | − | − | − | − | + (H) | − | + (I) | + (K) | + (D) | + (N) | − | + (N) |
a
Amino acids of seal influenza A(H10N7) virus unique to the outbreak strains are indicated in parentheses.