TABLE 3.
Comparison of seal influenza A(H10N7) virus internal gene segment amino acid sequences at different stages of the outbreak and with Eurasian wild bird influenza A viruses and other seal influenza A viruses
| Influenza A virus | Amino acid at indicated positiona |
|||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PB1 |
PB1-F2 | PB2 |
PA |
M1 |
M2 |
NP |
NS1 |
NEP |
||||||||||||||||||||||||
| 14 | 62 | 76 | 94 | 154 | 273 | 453 | 577 | 687 | 752 | 63 | 17 | 60 | 478 | 598 | 101 | 144 | 192 | 196 | 277 | 391 | 400 | 207 | ID | 52 | 329 | 450 | 55 | 81 | 94 | 171 | ID | |
| A/Seal/Sweden/SVA0546/2014 (April 2014) | V | R | D | F | G | I | S | R | R | E | S | C | D | V | T | D | H | H | K | A | R | S | N | ID | H | V | S | E | V | T | D | ID |
| A/harbor seal/Germany/S1047_14_L/2014 (October 2014) | V | R | N | S | S | I | S | R | R | E | P | C | D | V | T | D | H | H | K | A | R | S | S | ID | H | V | S | E | V | I | Y | ID |
| A/harbor seal/NL/PV14-221_ThS/2015 (January 2015) | V | R | N | S | G | I | S | R | R | D | P | C | D | V | A | D | Q | H | K | A | R | S | S | ID | H | M | S | K | V | T | Y | ID |
| Other seal influenza A viruses | A/ND | G | D | F | G | V | A | K | Q | E | S | R | D/N | I/V | T | ND/E/D | H | R | R | S | K/R | Q/S | S | NA | Y | V | N/S | E | I | T | D | NA |
| Amino acid unique to outbreak strain?b | − | − | − | − | − | − | + | − | − | + (D) | − | + | − | − | − | − | − | + | − | − | − | − | − | ID | − | − | − | − | − | − | − | ID |
a
ND, no data available for all seal influenza A viruses; ID, identical; NA, not applicable.
b
Amino acids of seal influenza A(H10N7) viruses that were not detected in Eurasian avian influenza virus sequences are indicated in parentheses.