TABLE 4.
Replication of H7N9 influenza viruses following ocular inoculation in mice
| Tissue | Day p.i. | Virus titera |
|||
|---|---|---|---|---|---|
| Anhui/1/13b | Taiwan/1/13 | HK/5942/13 | BC/1/15 | ||
| Eye | 3 | 1.5 (1/7) | 2.1 ± 0.1 | 2.9 ± 0.3 | 1.9 ± 0.5 (2/4) |
| Nose | 3 | 2.7 ± 0.9 (4/7) | 3.9 ± 0.8 | 2.3 ± 0.5 | 2.5 ± 0.4 (3/4) |
| Lung | 3 | 0/7 | 2.1 (1/3) | 1.4 ± 0.1 | 2.2 ± 0.7 (3/4) |
| Eye | 6 | 2.1 ± 1.2 (2/7) | 2.1 ± 0.5 | 2.2 ± 0.1 | 1.4 ± 0.2 (3/4) |
| Nose | 6 | 2.8 ± 0.8 (6/7) | 2.8 ± 0.6 | 2.7 ± 1.2 | 3.4 ± 0.2 |
| Lung | 6 | 1.6 (1/7) | 1.5 (2/3) | 5.1 ± 0.5 (2/3) | 2.0 ± 0.6 (3/4) |
a
Mean virus titers in mice inoculated with 106 PFU/5 μl of virus following corneal scarification. Virus titers are expressed as the mean log10 PFU/ml ± SD among mice with positive virus detection (data are representative of all mice examined unless denoted in parentheses, in which the number of mice with positive virus detection/total number of mice in the group is indicated). The limit of virus detection was 10 PFU.
b
Includes data published previously in reference 28.