FIG 5.

Association of age with breadth of neutralization. We compared the ages of the individuals in the broadly and narrowly neutralizing groups in the full CHCV cohort tested against panel XG (A) and in the broadly and narrowly neutralizing gt1 subgroups tested against panel Gt1 (B) as characterized in Fig. 2. Similarly, the broadly and narrowly neutralizing groups were compared for duration of infection (estimated) and age at acquisition (estimated) in both the full CHCV cohort (C and E) and the gt1 subgroup (D and F). Note that no data were available for 6 broadly and 10 narrowly neutralizing individuals in the full CHCV cohort and 4 broadly and 4 narrowly neutralizing individuals in the gt1 subgroup. Statistical comparisons between the groups were conducted using the Mann-Whitney U test.