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. Author manuscript; available in PMC: 2017 Mar 24.
Published in final edited form as: J Med Chem. 2016 Mar 15;59(6):2579–2595. doi: 10.1021/acs.jmedchem.5b01780

Table 3.

atRA concentration in cell media after 24 hour treatment

Treatments atRA in cell media (nM)
Vehicle 0.49 ± 0.33
100nM atRA 13.2 ± 0.14
1μM atRA 214 ± 13.6
1μM 22 1.09 ± 0.52
1μM 24 0.27 ± 0.09
100nM atRA + 1μM 22 45.5 ± 2.8*
100nM atRA + 1μM 24 25.6 ± 3.4*
100nM atRA + 1μM 30 113 ± 9*
*

significantly different from the 100 nM RA treatment