Table 1. Patient Characteristics.
ATG 5.1 | ATG 7.5 | |
---|---|---|
N | 19 | 22 |
Male | 12 | 14 |
Median age (range) | 57 (44-69) | 57 (40-68) |
Donor | ||
Matched related donor | 9 | 10 |
Unrelated donor | 10 | 12 |
HLA Mismatch | 2 | 2 |
Stem cell source | ||
Bone marrow | 2 | 2 |
Peripheral blood | 17 | 20 |
Diagnosis and prior therapy | ||
MM | 5 | 4 |
NHL | 7 | 8 |
AML | 1 | 3 |
MDS | 0 | 2 |
CLL | 4 | 3 |
PLL | 2 | 2 |
Median no. of prior regimens (range) | 4 (2-10) | 4 (1-15) |
Prior autologous SCT | 6 | 8 |
Median cell dose infused | ||
CD3+ × 106/kg (range) | 2.3 (.1-5.7) | 2.9 (.2-11.3) |
CD34+ × 108/kg (range) | 5.8 (1.7-10.4) | 5.1 (1.6-7.5) |
MM indicates multiple myeloma; NHL, non-Hodgkin lymphoma; AML, acute myelogenous leukemia; MDS, myelodysplastic syndrome; CLL, chronic lymphocytic leukemia; PLL, prolymphocytic leukemia.