Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Structures of the FDA-approved INSTIs (RAL, 1; EVG, 2; and DTG, 3) and heterobicyclic compounds of the current series (4). Colors highlight key functional features: metal-chelating triad of heteroatoms (red), halobenzyl rings (blue). The terminal ring of DTG and the corresponding 6-substituents described in the present work shown in green shading.
