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. 2016 Apr 18;82(9):2608–2619. doi: 10.1128/AEM.04031-15

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Copyright © 2016 Lehtovirta-Morley et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

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FIG 1 — Predicted mechanisms of cytoplasmic pH regulation in “Ca. Nitrosotalea devanaterra” based on the presence of putative functional genes in the genome. (1) Cation influx and proton efflux. kdp, potassium transporting P-type ATPase gene; mgtA, putative magnesium-transporting P-type ATPase gene; mntA, NRAMP-type divalent cation transporter (two copies) gene, Na⁺/solute transporter, Na⁺/hydrogen exchanger (two copies). (2) Proton consumption by metabolism: acetolactate decarboxylase, carbonic anhydrase. (3) Reduced permeability of the cell wall/cell membrane: cell surface glycosylation, GDGT-4-dominated membrane.