TABLE 3.
Microbial OTUs whose relative abundances were positively correlated with oxalate intakea
| Lowest assigned taxonomy | Taxonomic level | No. of OTU | Relative abundance with diet of: |
r | P | |
|---|---|---|---|---|---|---|
| 0% oxalate | 3% oxalate | |||||
| Oscillospira | Genus | 4 | 1 × 10−4 | 5.8 × 10−3 | 0.54 ± 0.037 | 0.009–0.037 |
| Oxalobacter | Genus | 1 | 6.39 × 10−5 | 5.24 × 10−4 | 0.54 | 0.031 |
| Clostridiales | Order | 16 | 9.13 × 10−6 | 1.03 × 10−3 | 0.52 ± 0.015 | 0.009–0.04 |
| Ruminococcus | Genus | 5 | 0 | 3.29 × 10−4 | 0.52 ± 0.015 | 0.031–0.038 |
| Allobaculum | Genus | 3 | 0 | 3.29 × 10−4 | 0.51 ± 0.017 | 0.031–0.034 |
| S24-7 | Family | 50 | 1.01 × 10−3 | 1.27 × 10−2 | 0.51 ± 0.007 | 0.009–0.041 |
| Lactobacillus | Genus | 1 | 0 | 2.44 × 10−5 | 0.51 | 0.031 |
| Oxalobacteraceae | Family | 1 | 5.48 × 10−5 | 6.09 × 10−4 | 0.51 | 0.032 |
| RF39 | Order | 1 | 0 | 1.22 × 10−5 | 0.51 | 0.031 |
| Bifidobacterium | Genus | 3 | 9.13 × 10−6 | 1.83 × 10−3 | 0.50 ± 0.022 | 0.031–0.04 |
| Unassigned | NA | 19 | 4.57 × 10−5 | 8.52 × 10−4 | 0.49 ± 0.007 | 0.031–0.044 |
| Ruminococcaceae | Family | 3 | 2.74 × 10−5 | 3.17 × 10−4 | 0.48 ± 0.02 | 0.031–0.044 |
| Lachnospiraceae | Family | 3 | 3.65 × 10−5 | 2.19 × 10−4 | 0.48 ± 0.017 | 0.031–0.043 |
| Rikenellaceae | Family | 4 | 9.13 × 10−6 | 1.87 × 10−3 | 0.48 ± 0.004 | 0.034–0.037 |
| Coprococcus | Genus | 1 | 0 | 2.44 × 10−5 | 0.48 | 0.034 |
| Proteus | Genus | 1 | 0 | 2.44 × 10−5 | 0.46 | 0.04 |
| Salinibacterium | Genus | 1 | 2.74 × 10−5 | 0 | −0.46 | 0.039 |
a
We tested 6,232 OTU. Comparisons were performed by Pearson correlation regression analysis with a false discovery rate (FDR) correction for multiple comparisons. For taxa with multiple OTU that were correlated with oxalate consumption, the average r values and the range of P values are given and the relative abundance refers to the group of OTU as a whole. NA, not applicable.