Increased numbers of total, differentiated, and activated fibrocytes are found in peripheral blood of asthmatic patients. Numbers of CD45+Col1+, CD45+Col1+CD34+, CD45+Col1+ α-SMA+, CD45+Col1+ Smad2/3+, CD45+Col1+p-Smad2/3+ and CD45+Col1+p-AKT+ fibrocytes were increased in asthmatic patients compared with those in control subjects. The solid box represents the mean, and the horizontal line represents the median for each group. *Significant difference between asthmatic patients and respective control groups, P <.05.