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The concentration of circulating fibrocytes is associated with the increase in asthma severity. Numbers of circulating CD45+Col1+ (A) and CD45+Col1+CXCR4+ (B) fibrocytes in the GINAhigh group (GINA step 4 or 5) were significantly increased compared with those in both control subjects and the GINAlow group (GINA steps 1–3). *Significant difference between groups, P <.05.
