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. Author manuscript; available in PMC: 2016 Apr 19.
Published in final edited form as: Science. 2015 May 7;348(6237):910–914. doi: 10.1126/science.aab1601

Fig. 2. Single-cell ATAC-seq deconvolutes human cell type mixtures.

Fig. 2

(A–C): GM12878/HEK293T nuclei. (D–F): GM12878/HL-60 nuclei. (A & D) Histograms of proportions of reads mapping to cell-type specific DHSs that correspond to one cell type or the other. (B & E) Boxplots of the overall fraction of reads mapping to ENCODE-defined DHSs for individual cells. (C & F) Multidimensional scaling of single-cell ATAC-seq data using pairwise Jaccard distances between cells based on DHS usage. Cell type assignments based on proportions shown in A & D.