Table 2.

Food and water consumption per day.

	WT SD	WT HFHF-STZ	AT2R-KO SD	AT2R-KO HFHF-STZ
Mean water consumption (mL.day−1)	6.1 ± 0.2	4.8 ± 0.1a	5.4 ± 0.1a	5.1 ± 0.1
Mean food consumption (g.day−1)	4.5 ± 0.2	2.3 ± 0.1a	3.7 ± 0.1a	2.3 ± 0.1c
Mean caloric intake (kcal.day−1)	15.3 ± 0.8	11.2 ± 0.4a	12.7 ± 0.2a	11.6 ± 0.5c

Values are means ± SE from 9–10 animals per group. Wild-type (WT) and AT2R-knockout-out (KO) mice were fed for 6 weeks either with standard laboratory rodent diet (SD) or with a high-fat/high-fructose with small injection of streptozotocin (HFHF-STZ). Statistical analyses were performed using Mann-Whitney test. a: P < 0 .05 vs. WT SD; b: P < 0 .05 vs. WT HFHF-STZ ; c: P < 0 .05 vs. AT2R-KO SD.