MA binds with higher affinity to raft-like liposomes. (a)
1H NMR Spectra of HIV-1 MA and myr(−)MA in the presence of non-raft-like and raft-like liposomes. Colors correspond to protein alone (black); non-raft-like liposomes with no PI(4,5)P2 (red) or with 1mol% PI(4,5)P2 (green), and raft-like liposomes with no PI(4,5)P2 (orange) or 2.5mol% PI(4,5)P2 (cyan). (b) Fraction of MA mutants bound to liposomes containing different membrane compositions.