Table 2.

Number and percent of patients who refused clinical trial participation by reasons for refusal, overall and by race

	African-American, n = 130	White, n = 216	Total, N = 346
	n (%)	n (%)	N (%)
Extra financial or logistical burden*	13 (10.0)	48 (22.2)	61 (17.6)
Lack of interest in trial*	33 (25.4)	26 (12.0)	59 (17.0)
Avoidance of specific treatment	15 (11.5)	24 (11.1)	39 (11.3)
Preference for specific treatment**	10 (7.7)	28 (13.0)	38 (11.0)
Fear of toxicity/side effects	9 (6.9)	21 (9.7)	30 (8.7)
Discomfort with randomization***	6 (4.6)	20 (9.3)	26 (7.5)
Physician barrier	6 (4.6)	16 (7.4)	22 (6.4)
Overwhelmed physically or emotionally	8 (6.1)	6 (2.8)	14 (4.0)
Pressure from family/cultural factors***	9 (6.9)	5 (2.3)	14 (4.0)
Seen only for a second opinion	0 (0.0)	1 (0.46)	1 (0.29)
No reason provided**	21 (16.1)	21 (9.7)	42 (12.1)

^*Chi-squared test, p <0.0001.

^**Chi-squared test, 0.001 > p <0.0001.

^***Chi-squared test 0.05 > p <0.001.