Table 3. Cox proportional hazards regression analysis measured hazard ratio of irritable bowel syndrome for asthma patients by treatment.
| Crude HR | Adjusted HR† | |||||
|---|---|---|---|---|---|---|
| Variables | N | Events | PY | Rate# | (95% CI) | (95% CI) |
| Treatments of asthma | ||||||
| Non-ICS user | 17039 | 965 | 112256 | 8.60 | 1 (Reference) | 1 (Reference) |
| ICS user | 12609 | 707 | 90202 | 7.84 | 0.92 (0.84–1.02) | 0.93 (0.84–1.03) |
Crude HR = relative hazard ratio, CI = confidence interval, ICS = inhaled corticosteroids;
Rate#, incidence rate per 1000 person-years;
† Model was adjusted for age, sex, and comorbidities of COPD, GERD, allergic rhinitis, chronic sinusitis, atopic dermatitis, anxiety, depression, and obesity.