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. 2016 Apr 12;353:i1246. doi: 10.1136/bmj.i1246

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Fig 7 Meta-analysis for mortality from coronary heart disease in trials testing replacement of saturated fat with vegetable oils rich in linoleic acid. Main analysis: trials provided replacement foods (vegetable oils) and were not confounded by any concomitant interventions. Sensitivity analysis: includes trials that provided advice only and/or were confounded by addition of n-3 EPA and DHA. Risk ratios were used as estimates of hazard ratios in MCE, RCOT, LA Vet, and MRC-Soy. MCE=Minnesota Coronary Experiment; SDHS=Sydney Diet Heart Study; RCOT=Rose Corn Oil Trial; LA Vet=Los Angeles Veterans Trial; MRC-Soy=Medical Research Council Soy Oil Trial; DART=Diet and Re-infarction Trial; ODHS=Oslo Diet Heart Study; STARS=St. Thomas Atherosclerosis Regression Study; LA=linoleic acid; SFA=saturated fat; ALA=α linolenic acid; EPA=eicosapentaenoate; DHA=docosahexaenoate